TY  - GEN
AU  - Feldkamp,M M
AU  - Lau,N
AU  - Roncari,L
AU  - Guha,A
TI  - Isotype-specific Ras.GTP-levels predict the efficacy of farnesyl transferase inhibitors against human astrocytomas regardless of Ras mutational status
SN  - 0008-5472
PY  - 2001///0621
KW  - Alkyl and Aryl Transferases
KW  - antagonists & inhibitors
KW  - Animals
KW  - Astrocytoma
KW  - drug therapy
KW  - Brain Neoplasms
KW  - Cell Division
KW  - drug effects
KW  - Enzyme Inhibitors
KW  - pharmacology
KW  - Farnesyltranstransferase
KW  - Genes, ras
KW  - genetics
KW  - Glioblastoma
KW  - Guanosine Triphosphate
KW  - metabolism
KW  - Humans
KW  - Immunohistochemistry
KW  - Mice
KW  - Mice, Inbred BALB C
KW  - Mice, Inbred NOD
KW  - Mice, Nude
KW  - Mice, SCID
KW  - Monomeric GTP-Binding Proteins
KW  - Mutation
KW  - Piperidines
KW  - Pyridines
KW  - Tumor Cells, Cultured
KW  - Xenograft Model Antitumor Assays
KW  - ras Proteins
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
ER  -