Heat shock protein 27 is a substrate of cGMP-dependent protein kinase in intact human platelets: phosphorylation-induced actin polymerization caused by HSP27 mutants. [electronic resource]
- The Journal of biological chemistry Mar 2001
- 7108-13 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0021-9258
10.1074/jbc.m009234200 doi
Actins--metabolism Binding Sites Blood Platelets--metabolism Blotting, Western Cyclic GMP--analogs & derivatives Cyclic GMP-Dependent Protein Kinases--chemistry Electrophoresis, Gel, Two-Dimensional Electrophoresis, Polyacrylamide Gel HSP27 Heat-Shock Proteins Heat-Shock Proteins Humans Intracellular Signaling Peptides and Proteins Mass Spectrometry Mitogen-Activated Protein Kinases--metabolism Molecular Chaperones Mutagenesis, Site-Directed Neoplasm Proteins--chemistry Phosphorylation Platelet Aggregation Protein Serine-Threonine Kinases--metabolism Serine--chemistry Signal Transduction Spectrometry, Fluorescence Spectrometry, Mass, Electrospray Ionization Substrate Specificity Thionucleotides--pharmacology Threonine--chemistry Time Factors p38 Mitogen-Activated Protein Kinases