TY  - GEN
AU  - Lee,M K
AU  - Jenkins,J L
AU  - You,T H
AU  - Curtiss,A
AU  - Son,J J
AU  - Adang,M J
AU  - Dean,D H
TI  - Mutations at the arginine residues in alpha8 loop of Bacillus thuringiensis delta-endotoxin Cry1Ac affect toxicity and binding to Manduca sexta and Lymantria dispar aminopeptidase N
SN  - 0014-5793
PY  - 2001///0705
KW  - Amino Acid Substitution
KW  - Aminopeptidases
KW  - metabolism
KW  - Animals
KW  - Bacillus thuringiensis
KW  - Bacillus thuringiensis Toxins
KW  - Bacterial Proteins
KW  - genetics
KW  - Bacterial Toxins
KW  - Binding, Competitive
KW  - drug effects
KW  - Biological Assay
KW  - Cell Membrane
KW  - chemistry
KW  - Digestive System
KW  - Endotoxins
KW  - Hemolysin Proteins
KW  - Insect Proteins
KW  - Larva
KW  - Lepidoptera
KW  - Manduca
KW  - Microvilli
KW  - Models, Molecular
KW  - Mutagenesis, Site-Directed
KW  - Pest Control, Biological
KW  - Protein Binding
KW  - Protein Structure, Tertiary
KW  - physiology
KW  - Structure-Activity Relationship
KW  - Surface Plasmon Resonance
N1  - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1016/s0014-5793(01)02446-2
ER  -