TY - GEN AU - Suzuki,A AU - Yamaguchi,M T AU - Ohteki,T AU - Sasaki,T AU - Kaisho,T AU - Kimura,Y AU - Yoshida,R AU - Wakeham,A AU - Higuchi,T AU - Fukumoto,M AU - Tsubata,T AU - Ohashi,P S AU - Koyasu,S AU - Penninger,J M AU - Nakano,T AU - Mak,T W TI - T cell-specific loss of Pten leads to defects in central and peripheral tolerance SN - 1074-7613 PY - 2001///0719 KW - Animals KW - Apoptosis KW - immunology KW - CD4-Positive T-Lymphocytes KW - cytology KW - Cell Division KW - Cytokines KW - biosynthesis KW - DNA-Binding Proteins KW - metabolism KW - Enterotoxins KW - Female KW - Genes, Tumor Suppressor KW - I-kappa B Proteins KW - Immune Tolerance KW - Lymphatic Diseases KW - Lymphoma, T-Cell KW - Male KW - Mice KW - Mice, Inbred C57BL KW - Mice, Knockout KW - Mice, Transgenic KW - Mitogen-Activated Protein Kinases KW - PTEN Phosphohydrolase KW - Phosphoric Monoester Hydrolases KW - genetics KW - Protein Serine-Threonine Kinases KW - Proto-Oncogene Proteins KW - Proto-Oncogene Proteins c-akt KW - Proto-Oncogene Proteins c-bcl-2 KW - Receptors, Antigen KW - Receptors, Antigen, T-Cell KW - Splenomegaly KW - Staphylococcus aureus KW - Superantigens KW - Thymus Gland KW - abnormalities KW - Tumor Suppressor Proteins N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/s1074-7613(01)00134-0 ER -