TY - GEN AU - Trimmer,E E AU - Ballou,D P AU - Ludwig,M L AU - Matthews,R G TI - Folate activation and catalysis in methylenetetrahydrofolate reductase from Escherichia coli: roles for aspartate 120 and glutamate 28 SN - 0006-2960 PY - 2001///0816 KW - Amino Acid Substitution KW - genetics KW - Asparagine KW - chemistry KW - Aspartic Acid KW - Catalysis KW - Enzyme Activation KW - Escherichia coli KW - enzymology KW - Folic Acid KW - Glutamic Acid KW - Glutamine KW - Kinetics KW - Methylenetetrahydrofolate Dehydrogenase (NAD+) KW - Methylenetetrahydrofolate Reductase (NADPH2) KW - Mutagenesis, Site-Directed KW - NAD KW - NAD(P)H Dehydrogenase (Quinone) KW - Oxidation-Reduction KW - Oxidoreductases KW - Oxidoreductases Acting on CH-NH Group Donors KW - antagonists & inhibitors KW - Spectrophotometry KW - methods KW - Vitamin K N1 - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1021/bi002790v ER -