TY  - GEN
AU  - Moriyama,T
AU  - Wada,M
AU  - Urade,R
AU  - Kito,M
AU  - Katunuma,N
AU  - Ogawa,T
AU  - Simoni,R D
TI  - 3-hydroxy-3-methylglutaryl coenzyme A reductase is sterol-dependently cleaved by cathepsin L-type cysteine protease in the isolated endoplasmic reticulum
SN  - 0003-9861
PY  - 2001///0607
KW  - Acetylcysteine
KW  - analogs & derivatives
KW  - Animals
KW  - Cathepsin L
KW  - Cathepsins
KW  - antagonists & inhibitors
KW  - Cell Extracts
KW  - Cell Line
KW  - Cell Membrane Permeability
KW  - Cricetinae
KW  - Cysteine Endopeptidases
KW  - isolation & purification
KW  - Endopeptidases
KW  - Endoplasmic Reticulum
KW  - enzymology
KW  - Epoxy Compounds
KW  - pharmacology
KW  - Hydrogen-Ion Concentration
KW  - Hydroxymethylglutaryl CoA Reductases
KW  - metabolism
KW  - Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent
KW  - Intracellular Membranes
KW  - drug effects
KW  - Leucine
KW  - Lysosomes
KW  - Multienzyme Complexes
KW  - Protease Inhibitors
KW  - Proteasome Endopeptidase Complex
KW  - Protein Processing, Post-Translational
KW  - Pyridines
KW  - Sonication
KW  - Sterols
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1006/abbi.2000.2209
ER  -