TY - GEN AU - Jisaka,M AU - Boeglin,W E AU - Kim,R B AU - Brash,A R TI - Site-directed mutagenesis studies on a putative fifth iron ligand of mouse 8S-lipoxygenase: retention of catalytic activity on mutation of serine-558 to asparagine, histidine, or alanine SN - 0003-9861 PY - 2001///0607 KW - Amino Acid Sequence KW - Amino Acid Substitution KW - genetics KW - Animals KW - Arachidonate Lipoxygenases KW - chemistry KW - Base Sequence KW - Blotting, Western KW - Catalysis KW - Chromatography, High Pressure Liquid KW - Conserved Sequence KW - HeLa Cells KW - Humans KW - Hydroxyeicosatetraenoic Acids KW - metabolism KW - Iron KW - Ligands KW - Linoleic Acids KW - Linoleic Acids, Conjugated KW - Mice KW - Mutagenesis, Site-Directed KW - Structure-Activity Relationship N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1006/abbi.2000.2175 ER -