TY  - GEN
AU  - Ponnappa,B C
AU  - Dey,I
AU  - Tu ,G C
AU  - Zhou,F
AU  - Aini,M
AU  - Cao ,Q N
AU  - Israel,Y
TI  - In vivo delivery of antisense oligonucleotides in pH-sensitive liposomes inhibits lipopolysaccharide-induced production of tumor necrosis factor-alpha in rats
SN  - 0022-3565
PY  - 2001///0614
KW  - Animals
KW  - Chemical and Drug Induced Liver Injury
KW  - Dose-Response Relationship, Drug
KW  - Drug Delivery Systems
KW  - methods
KW  - Drug Stability
KW  - Endosomes
KW  - Hydrogen-Ion Concentration
KW  - In Vitro Techniques
KW  - Injections, Intravenous
KW  - Lipopolysaccharides
KW  - pharmacology
KW  - Liposomes
KW  - Liver
KW  - drug effects
KW  - Liver Diseases
KW  - metabolism
KW  - Male
KW  - Oligonucleotides, Antisense
KW  - administration & dosage
KW  - Organothiophosphorus Compounds
KW  - Phosphorothioate Oligonucleotides
KW  - RNA, Messenger
KW  - antagonists & inhibitors
KW  - Rats
KW  - Rats, Sprague-Dawley
KW  - Spleen
KW  - Tissue Distribution
KW  - Treatment Outcome
KW  - Tumor Necrosis Factor-alpha
N1  - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S
ER  -