TY  - GEN
AU  - van Kuilenburg,A B
AU  - Muller,E W
AU  - Haasjes,J
AU  - Meinsma,R
AU  - Zoetekouw,L
AU  - Waterham,H R
AU  - Baas,F
AU  - Richel,D J
AU  - van Gennip,A H
TI  - Lethal outcome of a patient with a complete dihydropyrimidine dehydrogenase (DPD) deficiency after administration of 5-fluorouracil: frequency of the common IVS14+1G>A mutation causing DPD deficiency
SN  - 1078-0432
PY  - 2001///0719
KW  - Adult
KW  - Antimetabolites, Antineoplastic
KW  - metabolism
KW  - Dihydrouracil Dehydrogenase (NADP)
KW  - Exons
KW  - genetics
KW  - Fatal Outcome
KW  - Female
KW  - Fibroblasts
KW  - enzymology
KW  - Fluorouracil
KW  - Gene Frequency
KW  - Humans
KW  - Leukocytes, Mononuclear
KW  - Mutation
KW  - Oxidoreductases
KW  - deficiency
KW  - Polymorphism, Restriction Fragment Length
KW  - Thymine
KW  - blood
KW  - Uracil
N1  - Publication Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't
ER  -