TY  - GEN
AU  - Löthgren,A
AU  - McCartney,M
AU  - Rupp Thuresson,E
AU  - James,S R
TI  - A model of activation of the protein tyrosine phosphatase SHP-2 by the human leptin receptor
SN  - 0006-3002
PY  - 2001///0607
KW  - Binding Sites
KW  - Carrier Proteins
KW  - chemistry
KW  - Catalytic Domain
KW  - Enzyme Activation
KW  - Escherichia coli
KW  - Humans
KW  - Intracellular Signaling Peptides and Proteins
KW  - Kinetics
KW  - Models, Chemical
KW  - Neuroblastoma
KW  - pathology
KW  - Peptide Fragments
KW  - metabolism
KW  - Phosphorylation
KW  - Phosphotyrosine
KW  - Protein Binding
KW  - drug effects
KW  - Protein Conformation
KW  - Protein Processing, Post-Translational
KW  - Protein Structure, Tertiary
KW  - Protein Tyrosine Phosphatase, Non-Receptor Type 11
KW  - Protein Tyrosine Phosphatase, Non-Receptor Type 6
KW  - Protein Tyrosine Phosphatases
KW  - Receptors, Cell Surface
KW  - Receptors, Leptin
KW  - Recombinant Fusion Proteins
KW  - SH2 Domain-Containing Protein Tyrosine Phosphatases
KW  - Signal Transduction
KW  - Tumor Cells, Cultured
KW  - Vanadates
KW  - pharmacology
KW  - src Homology Domains
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/s0167-4838(00)00257-0
ER  -