TY - GEN AU - Han,X AU - Sun,Y AU - Scott,S AU - Bleich,D TI - Tissue inhibitor of metalloproteinase-1 prevents cytokine-mediated dysfunction and cytotoxicity in pancreatic islets and beta-cells SN - 0012-1797 PY - 2001///0521 KW - Animals KW - Apoptosis KW - drug effects KW - Cell Survival KW - Cells, Cultured KW - Cytokines KW - antagonists & inhibitors KW - DNA Fragmentation KW - Flow Cytometry KW - Gene Expression Regulation, Enzymologic KW - Genes, Reporter KW - Glucose KW - pharmacology KW - In Vitro Techniques KW - Insulin KW - metabolism KW - Insulin Secretion KW - Interferon-gamma KW - toxicity KW - Interleukin-1 KW - Islets of Langerhans KW - cytology KW - Luciferases KW - genetics KW - Mice KW - NF-kappa B KW - Nitric Oxide Synthase KW - Nitric Oxide Synthase Type II KW - Rats KW - Recombinant Proteins KW - Tissue Inhibitor of Metalloproteinase-1 KW - Tissue Inhibitor of Metalloproteinase-2 KW - Transfection KW - Tumor Necrosis Factor-alpha N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.2337/diabetes.50.5.1047 ER -