TY  - GEN
AU  - Yoshikawa,H
AU  - Matsubara,K
AU  - Qian,G S
AU  - Jackson,P
AU  - Groopman,J D
AU  - Manning,J E
AU  - Harris,C C
AU  - Herman,J G
TI  - SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity
SN  - 1061-4036
PY  - 2001///0531
KW  - Antineoplastic Agents
KW  - therapeutic use
KW  - Carcinoma, Hepatocellular
KW  - genetics
KW  - Carrier Proteins
KW  - CpG Islands
KW  - DNA Methylation
KW  - DNA-Binding Proteins
KW  - metabolism
KW  - Gene Silencing
KW  - Genes, Tumor Suppressor
KW  - Genetic Therapy
KW  - Humans
KW  - Intracellular Signaling Peptides and Proteins
KW  - Janus Kinase 2
KW  - Liver Neoplasms
KW  - Molecular Sequence Data
KW  - Protein-Tyrosine Kinases
KW  - antagonists & inhibitors
KW  - Proto-Oncogene Proteins
KW  - Repressor Proteins
KW  - STAT3 Transcription Factor
KW  - Signal Transduction
KW  - Suppressor of Cytokine Signaling 1 Protein
KW  - Suppressor of Cytokine Signaling Proteins
KW  - Trans-Activators
KW  - Tyrphostins
N1  - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1038/ng0501-29
ER  -