TY  - GEN
AU  - Ozawa,S
AU  - Ohta,K
AU  - Miyajima,A
AU  - Kurebayashi,H
AU  - Sunouchi,M
AU  - Shimizu,M
AU  - Murayama,N
AU  - Matsumoto,Y
AU  - Fukuoka,M
AU  - Ohno,Y
TI  - Metabolic activation of o-phenylphenol to a major cytotoxic metabolite, phenylhydroquinone: role of human CYP1A2 and rat CYP2C11/CYP2E1
SN  - 0049-8254
PY  - 2001///0628
KW  - Animals
KW  - Aryl Hydrocarbon Hydroxylases
KW  - Biotransformation
KW  - Biphenyl Compounds
KW  - pharmacokinetics
KW  - Cytochrome P-450 CYP1A2
KW  - metabolism
KW  - Cytochrome P-450 CYP2E1
KW  - Cytochrome P-450 Enzyme System
KW  - Cytochrome P450 Family 2
KW  - Cytochromes
KW  - Flavonoids
KW  - Humans
KW  - Hydroquinones
KW  - Hydroxylation
KW  - Isoenzymes
KW  - Kinetics
KW  - Liver Neoplasms, Experimental
KW  - Male
KW  - Microsomes, Liver
KW  - enzymology
KW  - Phenols
KW  - Polymers
KW  - Polyphenols
KW  - Rats
KW  - Rats, Inbred F344
KW  - Rats, Sprague-Dawley
KW  - Recombinant Proteins
KW  - Steroid 16-alpha-Hydroxylase
KW  - Steroid Hydroxylases
KW  - Tumor Cells, Cultured
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1080/00498250050200159
ER  -