Rational design of a potent, long-lasting form of interferon: a 40 kDa branched polyethylene glycol-conjugated interferon alpha-2a for the treatment of hepatitis C. [electronic resource]
- Bioconjugate chemistry
- 195-202 p. digital
Publication Type: Journal Article
1043-1802
10.1021/bc000082g doi
Animals Antineoplastic Agents--chemical synthesis Antiviral Agents--chemical synthesis Cell Line Clinical Trials, Phase II as Topic Clinical Trials, Phase III as Topic Drug Design Drug Screening Assays, Antitumor Female Hepatitis C--drug therapy Humans Immunoblotting Interferon alpha-2 Interferon-alpha--chemical synthesis Mice Mice, Nude Molecular Structure Neoplasms--drug therapy Polyethylene Glycols--chemical synthesis Rats Rats, Sprague-Dawley Recombinant Proteins Vesicular stomatitis Indiana virus--drug effects