TY  - GEN
AU  - Vagnoni,L M
AU  - Gronostaj,M
AU  - Kerrigan,J E
TI  - 6-Acylamino-2-1[(ethylsulfonyl)oxy]-1H-isoindole-1,3-diones mechanism-based inhibitors of human leukocyte elastase and cathepsin G: effect of chirality in the 6-acylamino substituent on inhibitory potency and selectivity
SN  - 0968-0896
PY  - 2001///1101
KW  - Animals
KW  - Cathepsin G
KW  - Cathepsins
KW  - antagonists & inhibitors
KW  - Cattle
KW  - Chymotrypsin
KW  - Drug Stability
KW  - Enzyme Inhibitors
KW  - chemical synthesis
KW  - Humans
KW  - Indoles
KW  - Kinetics
KW  - Leukocyte Elastase
KW  - Models, Molecular
KW  - Pancreatic Elastase
KW  - Serine Endopeptidases
KW  - Stereoisomerism
KW  - Structure-Activity Relationship
KW  - Substrate Specificity
KW  - Swine
KW  - Thermodynamics
N1  - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/s0968-0896(00)00281-9
ER  -