Lin, A W

Oncogenic ras activates the ARF-p53 pathway to suppress epithelial cell transformation. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Apr 2001 - 5025-30 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0027-8424

10.1073/pnas.091100298 doi


Animals
Animals, Newborn
Calcium--pharmacology
Carcinoma, Squamous Cell--genetics
Cell Cycle
Cell Differentiation--drug effects
Cell Size--drug effects
Cell Transformation, Neoplastic
Cells, Cultured
Cyclin-Dependent Kinase Inhibitor p16--metabolism
DNA--biosynthesis
Gene Deletion
Keratinocytes--cytology
Mice
Mice, Nude
Neoplasm Transplantation
Nuclear Matrix--metabolism
Nuclear Proteins
Oncogene Protein p21(ras)--metabolism
Protein Transport
Proteins--genetics
Proto-Oncogene Proteins--metabolism
Proto-Oncogene Proteins c-mdm2
Signal Transduction
Tumor Suppressor Protein p14ARF
Tumor Suppressor Protein p53--deficiency