Zhang, L
Biochemical characterization of the gamma-secretase activity that produces beta-amyloid peptides. [electronic resource]
- Biochemistry Apr 2001
- 5049-55 p. digital
Publication Type: Journal Article
ISSN: 0006-2960
Standard No.: 10.1021/bi0028800 doi
Subjects--Topical Terms: Alzheimer Disease--enzymology Amyloid Precursor Protein Secretases Amyloid beta-Peptides--antagonists & inhibitors Aspartic Acid Endopeptidases Brefeldin A--pharmacology Cell Line Cell Membrane--enzymology Cell-Free System Endopeptidases--chemistry Enzyme Activation--drug effects Humans Hydrolysis Leupeptins--pharmacology Membrane Proteins--antagonists & inhibitors Oligopeptides--pharmacology Peptide Fragments--antagonists & inhibitors Protease Inhibitors--pharmacology Protein Transport--drug effects Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Substrate Specificity