Sapkota, G P <br/><br/>
Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP-dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell vrowth.  [electronic resource] 

 -  The Journal of biological chemistry  Jun 2001 
 - 19469-82 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0021-9258 
<br/><br/><label>Standard No.: </label>10.1074/jbc.M009953200  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>AMP-Activated Protein Kinase Kinases<br/>AMP-Activated Protein Kinases<br/>Animals<br/>Binding Sites<br/>Calcium-Calmodulin-Dependent Protein Kinases--metabolism<br/>Cell Division<br/>Cell Line<br/>Cloning, Molecular<br/>Colforsin--pharmacology<br/>Cyclic AMP--metabolism<br/>Cyclic AMP-Dependent Protein Kinases--metabolism<br/>Cysteine--chemistry<br/>Enzyme Activation<br/>Enzyme Inhibitors--pharmacology<br/>Epidermal Growth Factor--metabolism<br/>Glutathione Transferase--metabolism<br/>Humans<br/>Immunoblotting<br/>Isoquinolines--pharmacology<br/>Mevalonic Acid--pharmacology<br/>Mice<br/>Models, Biological<br/>Mutation<br/>Peutz-Jeghers Syndrome--genetics<br/>Phosphorylation<br/>Precipitin Tests<br/>Protein Prenylation<br/>Protein Serine-Threonine Kinases--genetics<br/>Rats<br/>Ribosomal Protein S6 Kinases--metabolism<br/>Ribosomal Protein S6 Kinases, 90-kDa<br/>Serine--chemistry<br/>Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization<br/>Sulfonamides<br/>Time Factors<br/>Transfection