Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein. [electronic resource]
- Science (New York, N.Y.) Apr 2001
- 104-6 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0036-8075
10.1126/science.1057991 doi
Aging--physiology Alleles Animals Body Constitution Carrier Proteins--genetics Crosses, Genetic Drosophila Proteins Drosophila melanogaster--genetics Female Fertility Genes, Insect Heterozygote Hot Temperature Insect Proteins--genetics Insulin--metabolism Insulin Receptor Substrate Proteins Intracellular Signaling Peptides and Proteins Longevity--physiology Male Mutation Oxidative Stress Protein-Tyrosine Kinases--genetics Receptor Protein-Tyrosine Kinases Receptor, Insulin--metabolism Reproduction Signal Transduction Somatomedins--metabolism Starvation Superoxide Dismutase