TY - GEN AU - Heddle,J G AU - Blance,S J AU - Zamble,D B AU - Hollfelder,F AU - Miller,D A AU - Wentzell,L M AU - Walsh,C T AU - Maxwell,A TI - The antibiotic microcin B17 is a DNA gyrase poison: characterisation of the mode of inhibition SN - 0022-2836 PY - 2001///0510 KW - Adenosine Triphosphate KW - metabolism KW - Adenylyl Imidodiphosphate KW - Anti-Bacterial Agents KW - chemistry KW - Anti-Infective Agents KW - pharmacology KW - Bacterial Proteins KW - Bacterial Toxins KW - Bacteriocins KW - Calcium KW - Ciprofloxacin KW - Coumarins KW - Cytotoxins KW - DNA Gyrase KW - DNA Replication KW - drug effects KW - DNA Topoisomerases, Type II KW - DNA, Superhelical KW - DNA-Directed DNA Polymerase KW - Escherichia coli KW - Kinetics KW - Models, Molecular KW - Mutation KW - genetics KW - Nucleic Acid Synthesis Inhibitors KW - Peptides KW - Protein Conformation KW - Quinolones KW - Substrate Specificity KW - Topoisomerase II Inhibitors KW - Yeasts KW - enzymology N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1006/jmbi.2001.4562 ER -