TY - GEN AU - Lunz,J G AU - Contrucci,S AU - Ruppert,K AU - Murase,N AU - Fung,J J AU - Starzl,T E AU - Demetris,A J TI - Replicative senescence of biliary epithelial cells precedes bile duct loss in chronic liver allograft rejection: increased expression of p21(WAF1/Cip1) as a disease marker and the influence of immunosuppressive drugs SN - 0002-9440 PY - 2001///0503 KW - Animals KW - Antibodies KW - pharmacology KW - Bile Ducts KW - pathology KW - Biomarkers KW - Cell Division KW - drug effects KW - Cellular Senescence KW - physiology KW - Chronic Disease KW - Cyclin-Dependent Kinase Inhibitor p21 KW - Cyclins KW - metabolism KW - Cyclosporine KW - Epithelial Cells KW - Graft Rejection KW - drug therapy KW - Humans KW - Immunosuppressive Agents KW - therapeutic use KW - Intracellular Membranes KW - Liver Transplantation KW - Male KW - Mice KW - RNA, Messenger KW - Signal Transduction KW - Tacrolimus KW - Time Factors KW - Transforming Growth Factor beta KW - genetics N1 - Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1016/S0002-9440(10)64089-8 ER -