TY  - GEN
AU  - Li,W
AU  - Fan,J
AU  - Bertino,J R
TI  - Selective sensitization of retinoblastoma protein-deficient sarcoma cells to doxorubicin by flavopiridol-mediated inhibition of cyclin-dependent kinase 2 kinase activity
SN  - 0008-5472
PY  - 2001///0426
KW  - Antibiotics, Antineoplastic
KW  - pharmacokinetics
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Antineoplastic Combined Chemotherapy Protocols
KW  - CDC2-CDC28 Kinases
KW  - Caspase 3
KW  - Caspases
KW  - metabolism
KW  - Cyclin A
KW  - antagonists & inhibitors
KW  - Cyclin-Dependent Kinase 2
KW  - Cyclin-Dependent Kinase Inhibitor p21
KW  - Cyclin-Dependent Kinases
KW  - Cyclins
KW  - biosynthesis
KW  - Doxorubicin
KW  - Drug Synergism
KW  - Enzyme Activation
KW  - drug effects
KW  - Enzyme Inhibitors
KW  - Flavonoids
KW  - G2 Phase
KW  - Humans
KW  - Osteosarcoma
KW  - drug therapy
KW  - Piperidines
KW  - Protein Serine-Threonine Kinases
KW  - Retinoblastoma Protein
KW  - deficiency
KW  - S Phase
KW  - Tumor Cells, Cultured
N1  - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S
ER  -