Li, W <br/><br/>
Selective sensitization of retinoblastoma protein-deficient sarcoma cells to doxorubicin by flavopiridol-mediated inhibition of cyclin-dependent kinase 2 kinase activity.  [electronic resource] 

 -  Cancer research  Mar 2001 
 - 2579-82 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>0008-5472 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antibiotics, Antineoplastic--pharmacokinetics<br/>Antineoplastic Agents--pharmacology<br/>Antineoplastic Combined Chemotherapy Protocols--pharmacology<br/>CDC2-CDC28 Kinases<br/>Caspase 3<br/>Caspases--metabolism<br/>Cyclin A--antagonists & inhibitors<br/>Cyclin-Dependent Kinase 2<br/>Cyclin-Dependent Kinase Inhibitor p21<br/>Cyclin-Dependent Kinases--antagonists & inhibitors<br/>Cyclins--biosynthesis<br/>Doxorubicin--pharmacokinetics<br/>Drug Synergism<br/>Enzyme Activation--drug effects<br/>Enzyme Inhibitors--pharmacology<br/>Flavonoids--pharmacology<br/>G2 Phase--drug effects<br/>Humans<br/>Osteosarcoma--drug therapy<br/>Piperidines--pharmacology<br/>Protein Serine-Threonine Kinases--antagonists & inhibitors<br/>Retinoblastoma Protein--deficiency<br/>S Phase--drug effects<br/>Tumor Cells, Cultured