Donald, S P Proline oxidase, encoded by p53-induced gene-6, catalyzes the generation of proline-dependent reactive oxygen species. [electronic resource] - Cancer research Mar 2001 - 1810-5 p. digital Publication Type: Journal Article ISSN: 0008-5472 Subjects--Topical Terms: Antibiotics, Antineoplastic--pharmacologyApoptosis--drug effectsCatalysisColonic Neoplasms--enzymologyDoxorubicin--pharmacologyEnzyme Induction--drug effectsGene Expression Regulation, Neoplastic--drug effectsHumansProline--metabolismProline Oxidase--biosynthesisRNA, Messenger--biosynthesisReactive Oxygen Species--metabolismTransfectionTumor Cells, CulturedTumor Suppressor Protein p53--geneticsUp-Regulation--drug effects