Versican V1 proteolysis in human aorta in vivo occurs at the Glu441-Ala442 bond, a site that is cleaved by recombinant ADAMTS-1 and ADAMTS-4. [electronic resource]
- The Journal of biological chemistry Apr 2001
- 13372-8 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0021-9258
10.1074/jbc.M009737200 doi
ADAM Proteins ADAMTS1 Protein ADAMTS4 Protein Alanine Aorta, Abdominal--metabolism Cells, Cultured Chondroitin Sulfate Proteoglycans--chemistry Disintegrins--metabolism Glutamic Acid Humans Lectins, C-Type Metalloendopeptidases--metabolism Molecular Sequence Data Muscle, Smooth, Vascular--metabolism Peptide Fragments--chemistry Procollagen N-Endopeptidase Proteoglycans--metabolism Recombinant Proteins--metabolism Substrate Specificity Tunica Intima--metabolism Versicans