TY - GEN AU - Choi,E K AU - Zaidi,N F AU - Miller,J S AU - Crowley,A C AU - Merriam,D E AU - Lilliehook,C AU - Buxbaum,J D AU - Wasco,W TI - Calsenilin is a substrate for caspase-3 that preferentially interacts with the familial Alzheimer's disease-associated C-terminal fragment of presenilin 2 SN - 0021-9258 PY - 2001///0726 KW - Alzheimer Disease KW - genetics KW - Animals KW - Apoptosis KW - Binding Sites KW - Blotting, Western KW - COS Cells KW - Calcium KW - metabolism KW - Calcium-Binding Proteins KW - chemistry KW - Caspase 3 KW - Caspases KW - Cell Membrane KW - Dose-Response Relationship, Drug KW - Enzyme Inhibitors KW - pharmacology KW - Humans KW - Kv Channel-Interacting Proteins KW - Membrane Proteins KW - Microscopy, Confocal KW - Microscopy, Fluorescence KW - Models, Biological KW - Mutagenesis, Site-Directed KW - Mutation KW - Phosphorylation KW - Precipitin Tests KW - Presenilin-2 KW - Protein Binding KW - Protein Structure, Tertiary KW - Repressor Proteins KW - Staurosporine KW - Subcellular Fractions KW - Transfection KW - Tumor Cells, Cultured N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1074/jbc.M008597200 ER -