TY - GEN AU - Deutsch,E AU - Dugray,A AU - AbdulKarim,B AU - Marangoni,E AU - Maggiorella,L AU - Vaganay,S AU - M'Kacher,R AU - Rasy,S D AU - Eschwege,F AU - Vainchenker,W AU - Turhan,A G AU - Bourhis,J TI - BCR-ABL down-regulates the DNA repair protein DNA-PKcs SN - 0006-4971 PY - 2001///0426 KW - Acetylcysteine KW - analogs & derivatives KW - Animals KW - Apoptosis KW - genetics KW - Blast Crisis KW - Child KW - Cysteine Endopeptidases KW - metabolism KW - DNA Repair KW - DNA, Neoplasm KW - DNA-Activated Protein Kinase KW - DNA-Binding Proteins KW - Enzyme Induction KW - Enzyme Inhibitors KW - pharmacology KW - Fusion Proteins, bcr-abl KW - physiology KW - Gene Expression Regulation, Leukemic KW - Humans KW - In Situ Hybridization, Fluorescence KW - Leukemia, Myelogenous, Chronic, BCR-ABL Positive KW - enzymology KW - Mice KW - Multienzyme Complexes KW - antagonists & inhibitors KW - Neuroblastoma KW - pathology KW - Nuclear Proteins KW - Oligopeptides KW - Precursor B-Cell Lymphoblastic Leukemia-Lymphoma KW - Protease Inhibitors KW - Proteasome Endopeptidase Complex KW - Protein Serine-Threonine Kinases KW - biosynthesis KW - Recombinant Fusion Proteins KW - Reverse Transcriptase Polymerase Chain Reaction KW - Transfection KW - Tumor Cells, Cultured KW - Tumor Stem Cell Assay KW - Tyrphostins N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1182/blood.v97.7.2084 ER -