TY - GEN AU - Imler,J L AU - Hoffmann,J A TI - Toll and Toll-like proteins: an ancient family of receptors signaling infection SN - 1398-1714 PY - 2001///0503 KW - Adaptor Proteins, Signal Transducing KW - Animals KW - Antigens, Differentiation KW - physiology KW - Autoantigens KW - immunology KW - Cell Adhesion Molecules KW - chemistry KW - DNA-Binding Proteins KW - Drosophila Proteins KW - Drosophila melanogaster KW - embryology KW - Gene Expression Regulation KW - I-kappa B Proteins KW - Immunity, Innate KW - Infections KW - Insect Proteins KW - Interleukin-1 Receptor-Associated Kinases KW - Larva KW - Lipopolysaccharide Receptors KW - Lipopolysaccharides KW - MAP Kinase Signaling System KW - Mammals KW - genetics KW - Membrane Glycoproteins KW - Membrane Proteins KW - Mice KW - Mice, Knockout KW - Multigene Family KW - Myeloid Differentiation Factor 88 KW - NF-kappa B KW - Peptidoglycan KW - pharmacology KW - Phosphorylation KW - Protein Kinases KW - Protein Processing, Post-Translational KW - Protein Structure, Tertiary KW - Receptors, Cell Surface KW - Receptors, Immunologic KW - Recombinant Fusion Proteins KW - Signal Transduction KW - Teichoic Acids KW - Toll-Like Receptor 4 KW - Toll-Like Receptor 5 KW - Toll-Like Receptor 6 KW - Toll-Like Receptor 9 KW - Toll-Like Receptors KW - Ubiquitins KW - metabolism N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review ER -