Xie, W

An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Mar 2001 - 3375-80 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0027-8424

10.1073/pnas.051014398 doi


Animals
Aryl Hydrocarbon Hydroxylases
Bile Acids and Salts--metabolism
Cell Line
Cell Nucleus
Chlorocebus aethiops
Cholestasis--metabolism
Cytochrome P-450 CYP3A
Cytochrome P-450 Enzyme System--metabolism
Enzyme Induction
Humans
Lithocholic Acid--administration & dosage
Mice
Mice, Knockout
Oxidoreductases, N-Demethylating--metabolism
Pregnane X Receptor
Rats
Receptors, Cytoplasmic and Nuclear--physiology
Receptors, Steroid--physiology
Substrate Specificity