TY  - GEN
AU  - Erlichman,C
AU  - Boerner,S A
AU  - Hallgren,C G
AU  - Spieker,R
AU  - Wang,X Y
AU  - James,C D
AU  - Scheffer,G L
AU  - Maliepaard,M
AU  - Ross,D D
AU  - Bible,K C
AU  - Kaufmann,S H
TI  - The HER tyrosine kinase inhibitor CI1033 enhances cytotoxicity of 7-ethyl-10-hydroxycamptothecin and topotecan by inhibiting breast cancer resistance protein-mediated drug efflux
SN  - 0008-5472
PY  - 2001///0222
KW  - ATP Binding Cassette Transporter, Subfamily G, Member 2
KW  - ATP-Binding Cassette Transporters
KW  - genetics
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Biological Transport
KW  - drug effects
KW  - Camptothecin
KW  - analogs & derivatives
KW  - Cell Cycle
KW  - Dose-Response Relationship, Drug
KW  - Drug Interactions
KW  - Drug Resistance, Neoplasm
KW  - Drug Synergism
KW  - Enzyme Inhibitors
KW  - ErbB Receptors
KW  - Humans
KW  - Irinotecan
KW  - Morpholines
KW  - Neoplasm Proteins
KW  - Neoplastic Stem Cells
KW  - Phosphorylation
KW  - Protein-Tyrosine Kinases
KW  - antagonists & inhibitors
KW  - Recombinant Fusion Proteins
KW  - Topoisomerase I Inhibitors
KW  - Topotecan
KW  - metabolism
KW  - Transfection
KW  - Tumor Cells, Cultured
KW  - Tumor Stem Cell Assay
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S
ER  -