TY  - GEN
AU  - Jimonet,P
AU  - Bohme,G A
AU  - Bouquerel,J
AU  - Boireau,A
AU  - Damour,D
AU  - Debono,M W
AU  - Genevois-Borella,A
AU  - Hardy,J C
AU  - Hubert,P
AU  - Manfré,F
AU  - Nemecek,P
AU  - Pratt,J
AU  - Randle,J C
AU  - Ribeill,Y
AU  - Stutzmann,J M
AU  - Vuilhorgne,M
AU  - Mignani,S
TI  - Bioisosteres of 9-carboxymethyl-4-oxo-imidazo[1,2-a]indeno-[1,2-e]pyrazin-2-carboxylic acid derivatives. Progress towards selective, potent in vivo AMPA antagonists with longer durations of action
SN  - 0960-894X
PY  - 2001///0510
KW  - Animals
KW  - Anticonvulsants
KW  - chemical synthesis
KW  - Combinatorial Chemistry Techniques
KW  - Disease Models, Animal
KW  - Excitatory Amino Acid Antagonists
KW  - Imidazoles
KW  - Inhibitory Concentration 50
KW  - Male
KW  - Mice
KW  - Oocytes
KW  - drug effects
KW  - Pyrazinamide
KW  - analogs & derivatives
KW  - Pyrazines
KW  - Receptors, AMPA
KW  - antagonists & inhibitors
KW  - Receptors, N-Methyl-D-Aspartate
KW  - Seizures
KW  - chemically induced
KW  - Structure-Activity Relationship
KW  - alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/s0960-894x(00)00592-8
ER  -