Jimonet, P <br/><br/>
Bioisosteres of 9-carboxymethyl-4-oxo-imidazo[1,2-a]indeno-[1,2-e]pyrazin-2-carboxylic acid derivatives. Progress towards selective, potent in vivo AMPA antagonists with longer durations of action.  [electronic resource] 

 -  Bioorganic & medicinal chemistry letters  Jan 2001 
 - 127-32 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0960-894X 
<br/><br/><label>Standard No.: </label>10.1016/s0960-894x(00)00592-8  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Anticonvulsants--chemical synthesis<br/>Combinatorial Chemistry Techniques<br/>Disease Models, Animal<br/>Excitatory Amino Acid Antagonists--chemical synthesis<br/>Imidazoles--chemical synthesis<br/>Inhibitory Concentration 50<br/>Male<br/>Mice<br/>Oocytes--drug effects<br/>Pyrazinamide--analogs & derivatives<br/>Pyrazines--chemical synthesis<br/>Receptors, AMPA--antagonists & inhibitors<br/>Receptors, N-Methyl-D-Aspartate--antagonists & inhibitors<br/>Seizures--chemically induced<br/>Structure-Activity Relationship<br/>alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid--antagonists & inhibitors