TY - GEN AU - Lindsten,T AU - Ross,A J AU - King,A AU - Zong,W X AU - Rathmell,J C AU - Shiels,H A AU - Ulrich,E AU - Waymire,K G AU - Mahar,P AU - Frauwirth,K AU - Chen,Y AU - Wei,M AU - Eng,V M AU - Adelman,D M AU - Simon,M C AU - Ma,A AU - Golden,J A AU - Evan,G AU - Korsmeyer,S J AU - MacGregor,G R AU - Thompson,C B TI - The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues SN - 1097-2765 PY - 2001///0322 KW - Abnormalities, Multiple KW - genetics KW - Animals KW - Apoptosis KW - drug effects KW - Brain KW - abnormalities KW - Cells, Cultured KW - Crosses, Genetic KW - Embryonic and Fetal Development KW - Etoposide KW - pharmacology KW - Female KW - Gene Deletion KW - Gene Targeting KW - Genes, Essential KW - Hematopoietic Stem Cells KW - metabolism KW - Histocytochemistry KW - Kidney KW - Lymphoid Tissue KW - Male KW - Membrane Proteins KW - Mice KW - Mice, Knockout KW - Phenotype KW - Proto-Oncogene Proteins KW - Proto-Oncogene Proteins c-bcl-2 KW - Spleen KW - Thymus Gland KW - bcl-2 Homologous Antagonist-Killer Protein KW - bcl-2-Associated X Protein KW - fas Receptor KW - physiology N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1016/s1097-2765(00)00136-2 ER -