Lindsten, T

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues. [electronic resource] - Molecular cell Dec 2000 - 1389-99 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

1097-2765

10.1016/s1097-2765(00)00136-2 doi


Abnormalities, Multiple--genetics
Animals
Apoptosis--drug effects
Brain--abnormalities
Cells, Cultured
Crosses, Genetic
Embryonic and Fetal Development--genetics
Etoposide--pharmacology
Female
Gene Deletion
Gene Targeting
Genes, Essential--genetics
Hematopoietic Stem Cells--metabolism
Histocytochemistry
Kidney--abnormalities
Lymphoid Tissue--abnormalities
Male
Membrane Proteins--genetics
Mice
Mice, Knockout
Phenotype
Proto-Oncogene Proteins--genetics
Proto-Oncogene Proteins c-bcl-2--genetics
Spleen--abnormalities
Thymus Gland--abnormalities
bcl-2 Homologous Antagonist-Killer Protein
bcl-2-Associated X Protein
fas Receptor--physiology