Pavlova, A <br/><br/>
Cystatin inhibition of cathepsin B requires dislocation of the proteinase occluding loop. Demonstration By release of loop anchoring through mutation of his110.  [electronic resource] 

 -  FEBS letters  Dec 2000 
 - 156-60 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0014-5793 
<br/><br/><label>Standard No.: </label>10.1016/s0014-5793(00)02337-1  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Alanine<br/>Amino Acid Substitution<br/>Cathepsin B--antagonists & inhibitors<br/>Cystatin C<br/>Cystatins--pharmacology<br/>Cysteine Proteinase Inhibitors--pharmacology<br/>Histidine<br/>Humans<br/>Kinetics<br/>Mutagenesis, Site-Directed<br/>Protein Structure, Secondary<br/>Recombinant Proteins--antagonists & inhibitors