TY  - GEN
AU  - Brown,G R
AU  - Hollinshead,D M
AU  - Stokes,E S
AU  - Waterson,D
AU  - Clarke,D S
AU  - Foubister,A J
AU  - Glossop,S C
AU  - McTaggart,F
AU  - Mirrlees,D J
AU  - Smith,G J
AU  - Wood,R
TI  - A novel series of 4-piperidinopyridine and 4-piperidinopyrimidine inhibitors of 2,3-oxidosqualene cyclase-lanosterol synthase
SN  - 0022-2623
PY  - 2001///0201
KW  - Administration, Oral
KW  - Animals
KW  - Anticholesteremic Agents
KW  - chemical synthesis
KW  - Cholesterol
KW  - biosynthesis
KW  - Chromatography, High Pressure Liquid
KW  - Enzyme Inhibitors
KW  - Female
KW  - In Vitro Techniques
KW  - Intramolecular Transferases
KW  - antagonists & inhibitors
KW  - Microsomes
KW  - drug effects
KW  - Piperazines
KW  - Piperidines
KW  - Pyridines
KW  - Pyrimidines
KW  - Rats
KW  - Structure-Activity Relationship
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1021/jm000139k
ER  -