Friedrichsen, B N

Growth hormone- and prolactin-induced proliferation of insulinoma cells, INS-1, depends on activation of STAT5 (signal transducer and activator of transcription 5). [electronic resource] - Molecular endocrinology (Baltimore, Md.) Jan 2001 - 136-48 p. digital

Publication Type: Journal Article

0888-8809

10.1210/mend.15.1.0576 doi


Animals
Animals, Newborn
Cell Division--drug effects
Cells, Cultured
Cyclic AMP-Dependent Protein Kinases--antagonists & inhibitors
Cyclin D2
Cyclins--analysis
DNA--biosynthesis
DNA-Binding Proteins--genetics
Enzyme Inhibitors--pharmacology
Gene Expression
Human Growth Hormone--pharmacology
Humans
Insulin--biosynthesis
Insulinoma--pathology
Islets of Langerhans--cytology
MAP Kinase Kinase Kinase 1
Milk Proteins
Mitogen-Activated Protein Kinases--antagonists & inhibitors
Mutation
Pancreatic Neoplasms--pathology
Phosphoinositide-3 Kinase Inhibitors
Prolactin--pharmacology
Protein Kinase C--antagonists & inhibitors
Protein Serine-Threonine Kinases--antagonists & inhibitors
Protein-Tyrosine Kinases--antagonists & inhibitors
RNA, Messenger--analysis
Rats
Receptors, Prolactin--genetics
STAT5 Transcription Factor
Signal Transduction
Trans-Activators--genetics
Transfection
Tumor Cells, Cultured
p38 Mitogen-Activated Protein Kinases