TY - GEN AU - Bednar,M M AU - Gross,C E AU - Russell,S R AU - Fuller,S P AU - Ahern,T P AU - Howard,D B AU - Falck,J R AU - Reddy,K M AU - Balazy,M TI - 16(R)-hydroxyeicosatetraenoic acid, a novel cytochrome P450 product of arachidonic acid, suppresses activation of human polymorphonuclear leukocyte and reduces intracranial pressure in a rabbit model of thromboembolic stroke SN - 0148-396X PY - 2001///0208 KW - Animals KW - Arachidonic Acid KW - metabolism KW - Cell Adhesion KW - drug effects KW - Cell Aggregation KW - Cytochrome P-450 Enzyme System KW - Drug Synergism KW - Fibrinolytic Agents KW - pharmacology KW - Humans KW - Hydroxyeicosatetraenoic Acids KW - Intracranial Embolism and Thrombosis KW - complications KW - Intracranial Pressure KW - Leukotriene B4 KW - antagonists & inhibitors KW - Neutrophils KW - Rabbits KW - Single-Blind Method KW - Stroke KW - etiology KW - Tissue Plasminogen Activator N1 - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S ER -