Mc Gee, M M <br/><br/>
Pyrrolo-1,5-benzoxazepines induce apoptosis in chronic myelogenous leukemia (CML) cells by bypassing the apoptotic suppressor bcr-abl.  [electronic resource] 

 -  The Journal of pharmacology and experimental therapeutics  Jan 2001 
 - 31-40 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0022-3565 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antineoplastic Agents--pharmacology<br/>Apoptosis<br/>Blotting, Western<br/>Caspase 3<br/>Caspases--metabolism<br/>Down-Regulation<br/>Drug Resistance, Neoplasm<br/>Drug Screening Assays, Antitumor<br/>Fusion Proteins, bcr-abl<br/>Humans<br/>Leukemia, Myelogenous, Chronic, BCR-ABL Positive--pathology<br/>Oncogene Proteins, Fusion--genetics<br/>Oxazepines--pharmacology<br/>Phosphorylation<br/>Poly(ADP-ribose) Polymerases--metabolism<br/>Protein-Tyrosine Kinases--metabolism<br/>Pyrroles--pharmacology<br/>Reactive Oxygen Species--metabolism<br/>Tumor Cells, Cultured