Khoshnan, A

The physical association of protein kinase C theta with a lipid raft-associated inhibitor of kappa B factor kinase (IKK) complex plays a role in the activation of the NF-kappa B cascade by TCR and CD28. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Dec 2000 - 6933-40 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0022-1767

10.4049/jimmunol.165.12.6933 doi


CD28 Antigens--genetics
CD3 Complex--physiology
CD4-Positive T-Lymphocytes--enzymology
Cells, Cultured
Enzyme Activation--immunology
Enzyme Inhibitors--metabolism
Gene Expression Regulation--immunology
Humans
I-kappa B Kinase
Isoenzymes--biosynthesis
Jurkat Cells--enzymology
Membrane Microdomains--enzymology
Membrane Proteins--metabolism
NF-kappa B--metabolism
Promoter Regions, Genetic--immunology
Protein Kinase C--biosynthesis
Protein Kinase C-theta
Protein Serine-Threonine Kinases--antagonists & inhibitors
Receptors, Antigen, T-Cell--physiology
Response Elements--immunology
Signal Transduction--immunology
Talin--metabolism