TY  - GEN
AU  - Bombardier,C
AU  - Laine,L
AU  - Reicin,A
AU  - Shapiro,D
AU  - Burgos-Vargas,R
AU  - Davis,B
AU  - Day,R
AU  - Ferraz,M B
AU  - Hawkey,C J
AU  - Hochberg,M C
AU  - Kvien,T K
AU  - Schnitzer,T J
TI  - Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group
SN  - 0028-4793
PY  - 2000///1130
KW  - Adult
KW  - Arthritis, Rheumatoid
KW  - drug therapy
KW  - Cardiovascular Diseases
KW  - mortality
KW  - Cyclooxygenase 2
KW  - Cyclooxygenase 2 Inhibitors
KW  - Cyclooxygenase Inhibitors
KW  - therapeutic use
KW  - Duodenal Obstruction
KW  - chemically induced
KW  - Female
KW  - Gastric Outlet Obstruction
KW  - Gastrointestinal Diseases
KW  - Gastrointestinal Hemorrhage
KW  - Humans
KW  - Isoenzymes
KW  - antagonists & inhibitors
KW  - Lactones
KW  - adverse effects
KW  - Male
KW  - Membrane Proteins
KW  - Middle Aged
KW  - Naproxen
KW  - Peptic Ulcer
KW  - Proportional Hazards Models
KW  - Prostaglandin-Endoperoxide Synthases
KW  - Sulfones
N1  - Publication Type: Clinical Trial; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1056/NEJM200011233432103
ER  -