Gomi, K

Prostaglandin E2 selectively enhances the IgE-mediated production of IL-6 and granulocyte-macrophage colony-stimulating factor by mast cells through an EP1/EP3-dependent mechanism. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Dec 2000 - 6545-52 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0022-1767

10.4049/jimmunol.165.11.6545 doi


Adjuvants, Immunologic--physiology
Animals
Bone Marrow Cells--immunology
Cell Degranulation--immunology
Cell Line
Cyclic AMP--physiology
Cytokines--biosynthesis
Dinoprostone--physiology
Drug Synergism
Granulocyte-Macrophage Colony-Stimulating Factor--biosynthesis
Immunoglobulin E--physiology
Interleukin-6--biosynthesis
Kinetics
Mast Cells--immunology
Mice
Mice, Inbred C57BL
Protein Isoforms--biosynthesis
Receptors, Prostaglandin E--biosynthesis
Receptors, Prostaglandin E, EP1 Subtype
Receptors, Prostaglandin E, EP3 Subtype
Second Messenger Systems--physiology
Up-Regulation--immunology
beta-N-Acetylhexosaminidases--biosynthesis