Nakayama, Y
Tamoxifen and gonadal steroids inhibit colon cancer growth in association with inhibition of thymidylate synthase, survivin and telomerase expression through estrogen receptor beta mediated system. [electronic resource]
- Cancer letters Dec 2000
- 63-71 p. digital
Publication Type: Journal Article
ISSN: 0304-3835
Standard No.: 10.1016/s0304-3835(00)00600-5 doi
Subjects--Topical Terms: Antineoplastic Agents, Hormonal--pharmacology Cell Division--drug effects Colonic Neoplasms--drug therapy Dehydroepiandrosterone--pharmacology Dose-Response Relationship, Drug Enzyme Inhibitors--pharmacology Estradiol--pharmacology Estrogen Receptor alpha Estrogen Receptor beta Fluorouracil--pharmacology Gene Expression--drug effects Gonadal Steroid Hormones--pharmacology Growth Inhibitors--pharmacology Humans Inhibitor of Apoptosis Proteins Ligands Microtubule-Associated Proteins Neoplasm Proteins Protein Biosynthesis Proteins--antagonists & inhibitors Quercetin--pharmacology Receptors, Estrogen--biosynthesis Receptors, Progesterone--biosynthesis Steroids--pharmacology Survivin Tamoxifen--pharmacology Telomerase--antagonists & inhibitors Testosterone--pharmacology Thymidylate Synthase--antagonists & inhibitors Tumor Cells, Cultured