TY - GEN AU - Baker,B M AU - Gagnon,S J AU - Biddison,W E AU - Wiley,D C TI - Conversion of a T cell antagonist into an agonist by repairing a defect in the TCR/peptide/MHC interface: implications for TCR signaling SN - 1074-7613 PY - 2000///1207 KW - Alanine KW - metabolism KW - Amino Acid Substitution KW - immunology KW - Cells, Cultured KW - Crystallography, X-Ray KW - Cytotoxicity Tests, Immunologic KW - Gene Products, tax KW - chemistry KW - Glycine KW - HLA-A2 Antigen KW - Humans KW - Ligands KW - Peptides KW - Proline KW - Protein Binding KW - Protein Folding KW - Receptors, Antigen, T-Cell, alpha-beta KW - agonists KW - Sarcosine KW - Signal Transduction KW - T-Lymphocytes, Cytotoxic KW - Thermodynamics KW - Ultracentrifugation KW - methods KW - Water N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1016/s1074-7613(00)00047-9 ER -