TY  - GEN
AU  - Jacobs,J J
AU  - Keblusek,P
AU  - Robanus-Maandag,E
AU  - Kristel,P
AU  - Lingbeek,M
AU  - Nederlof,P M
AU  - van Welsem,T
AU  - van de Vijver,M J
AU  - Koh,E Y
AU  - Daley,G Q
AU  - van Lohuizen,M
TI  - Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers
SN  - 1061-4036
PY  - 2000///1213
KW  - Adenocarcinoma
KW  - genetics
KW  - Animals
KW  - Breast Neoplasms
KW  - COS Cells
KW  - Carrier Proteins
KW  - Cell Cycle Proteins
KW  - Cell Transformation, Neoplastic
KW  - Cells, Cultured
KW  - Cellular Senescence
KW  - Chromosomes, Human, Pair 17
KW  - Cyclin-Dependent Kinase Inhibitor p16
KW  - DNA-Binding Proteins
KW  - E2F Transcription Factors
KW  - E2F1 Transcription Factor
KW  - Female
KW  - Fibroblasts
KW  - cytology
KW  - Gene Amplification
KW  - Gene Deletion
KW  - Gene Expression Regulation, Neoplastic
KW  - Genes, BRCA1
KW  - Humans
KW  - Mice
KW  - Neoplasm Proteins
KW  - biosynthesis
KW  - Neoplastic Syndromes, Hereditary
KW  - Nuclear Proteins
KW  - Oncogenes
KW  - Polycomb Repressive Complex 1
KW  - Promoter Regions, Genetic
KW  - Protein Biosynthesis
KW  - Proteins
KW  - Proto-Oncogene Proteins
KW  - Proto-Oncogene Proteins c-myc
KW  - antagonists & inhibitors
KW  - Proto-Oncogene Proteins p21(ras)
KW  - Repressor Proteins
KW  - Retinoblastoma-Binding Protein 1
KW  - T-Box Domain Proteins
KW  - Transcription Factor DP1
KW  - Transcription Factors
KW  - Transfection
KW  - Tumor Cells, Cultured
KW  - Tumor Suppressor Protein p14ARF
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1038/81583
ER  -