Jacobs, J J
Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers. [electronic resource]
- Nature genetics Nov 2000
- 291-9 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
ISSN: 1061-4036
Standard No.: 10.1038/81583 doi
Subjects--Topical Terms: Adenocarcinoma--genetics Animals Breast Neoplasms--genetics COS Cells Carrier Proteins--genetics Cell Cycle Proteins--genetics Cell Transformation, Neoplastic--genetics Cells, Cultured Cellular Senescence--genetics Chromosomes, Human, Pair 17--genetics Cyclin-Dependent Kinase Inhibitor p16 DNA-Binding Proteins E2F Transcription Factors E2F1 Transcription Factor Female Fibroblasts--cytology Gene Amplification Gene Deletion Gene Expression Regulation, Neoplastic Genes, BRCA1 Humans Mice Neoplasm Proteins--biosynthesis Neoplastic Syndromes, Hereditary--genetics Nuclear Proteins--genetics Oncogenes Polycomb Repressive Complex 1 Promoter Regions, Genetic Protein Biosynthesis Proteins--genetics Proto-Oncogene Proteins--genetics Proto-Oncogene Proteins c-myc--antagonists & inhibitors Proto-Oncogene Proteins p21(ras)--antagonists & inhibitors Repressor Proteins--genetics Retinoblastoma-Binding Protein 1 T-Box Domain Proteins--genetics Transcription Factor DP1 Transcription Factors--antagonists & inhibitors Transfection Tumor Cells, Cultured Tumor Suppressor Protein p14ARF