Underwood, D C
SB 239063, a p38 MAPK inhibitor, reduces neutrophilia, inflammatory cytokines, MMP-9, and fibrosis in lung. [electronic resource]
- American journal of physiology. Lung cellular and molecular physiology Nov 2000
- L895-902 p. digital
Publication Type: Journal Article
ISSN: 1040-0605
Standard No.: 10.1152/ajplung.2000.279.5.L895 doi
Subjects--Topical Terms: Animals Bleomycin--toxicity Cells, Cultured Cytokines--biosynthesis Disease Models, Animal Enzyme Inhibitors--pharmacology Guinea Pigs Humans Hypertension, Pulmonary--chemically induced Imidazoles--pharmacology Inflammation--physiopathology Interleukin 1 Receptor Antagonist Protein Interleukin-1--blood Interleukin-6--blood Interleukin-8--blood Lipopolysaccharides--toxicity Lung--drug effects Lung Diseases, Obstructive--physiopathology Male Matrix Metalloproteinase 9--metabolism Mitogen-Activated Protein Kinases--antagonists & inhibitors Neutrophils--drug effects Pulmonary Alveoli--drug effects Pulmonary Fibrosis--chemically induced Pyrimidines--pharmacology Rats Rats, Inbred Lew Sialoglycoproteins--blood Tumor Necrosis Factor-alpha--metabolism p38 Mitogen-Activated Protein Kinases