Blockade of the renin-angiotensin and endothelin systems on progressive renal injury. [electronic resource]
- Hypertension (Dallas, Tex. : 1979) Oct 2000
- 561-8 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1524-4563
10.1161/01.hyp.36.4.561 doi
Angiotensin Receptor Antagonists Angiotensin-Converting Enzyme Inhibitors--administration & dosage Animals Antihypertensive Agents--administration & dosage Blood Pressure--drug effects Collagen--genetics Disease Models, Animal Disease Progression Drug Therapy, Combination Endothelin Receptor Antagonists Endothelin-1--metabolism Glomerular Filtration Rate--drug effects Kidney--drug effects Male Nephrectomy Proteinuria--urine RNA, Messenger--metabolism Rats Rats, Sprague-Dawley Receptor, Angiotensin, Type 1 Receptor, Angiotensin, Type 2 Receptor, Endothelin A Receptor, Endothelin B Renal Insufficiency--drug therapy Renin-Angiotensin System--drug effects Severity of Illness Index Transforming Growth Factor beta--genetics