TY - GEN AU - Tian,Z AU - Shen,X AU - Feng,H AU - Gao,B TI - IL-1 beta attenuates IFN-alpha beta-induced antiviral activity and STAT1 activation in the liver: involvement of proteasome-dependent pathway SN - 0022-1767 PY - 2000///1103 KW - Adjuvants, Immunologic KW - physiology KW - Animals KW - Antiviral Agents KW - antagonists & inhibitors KW - Binding, Competitive KW - immunology KW - Carcinoma, Hepatocellular KW - Cysteine Endopeptidases KW - DNA-Binding Proteins KW - Enzyme Activation KW - Female KW - Humans KW - Immunosuppressive Agents KW - pharmacology KW - Injections, Intravenous KW - Interferon Type I KW - administration & dosage KW - Interferon-alpha KW - Interleukin-1 KW - Janus Kinase 1 KW - Kupffer Cells KW - Liver KW - enzymology KW - Mice KW - Mice, Inbred ICR KW - Multienzyme Complexes KW - Phosphorylation KW - Proteasome Endopeptidase Complex KW - Protein Biosynthesis KW - Protein-Tyrosine Kinases KW - metabolism KW - Proteins KW - Rats KW - STAT1 Transcription Factor KW - Signal Transduction KW - Spleen KW - TYK2 Kinase KW - Trans-Activators KW - Tumor Cells, Cultured KW - Tyrosine N1 - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.4049/jimmunol.165.7.3959 ER -