TY  - GEN
AU  - Woo,L L
AU  - Purohit,A
AU  - Malini,B
AU  - Reed,M J
AU  - Potter,B V
TI  - Potent active site-directed inhibition of steroid sulphatase by tricyclic coumarin-based sulphamates
SN  - 1074-5521
PY  - 2001///0105
KW  - Alanine
KW  - analogs & derivatives
KW  - Antineoplastic Agents
KW  - chemical synthesis
KW  - Arylsulfatases
KW  - antagonists & inhibitors
KW  - Binding Sites
KW  - Breast Neoplasms
KW  - drug therapy
KW  - Coumarins
KW  - Dehydroepiandrosterone Sulfate
KW  - metabolism
KW  - Dose-Response Relationship, Drug
KW  - Estrone
KW  - Female
KW  - Glycine
KW  - Heterocyclic Compounds, 3-Ring
KW  - Humans
KW  - Hydrogen Bonding
KW  - Kinetics
KW  - Microsomes
KW  - drug effects
KW  - Models, Molecular
KW  - Placenta
KW  - Postmenopause
KW  - Steryl-Sulfatase
KW  - Structure-Activity Relationship
KW  - Sulfatases
KW  - Sulfonamides
KW  - Sulfonic Acids
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/s1074-5521(00)00023-5
ER  -